Aaron Rodgers, Packers, threw for a career-high 408 yards and tied a career best with four touchdown passes to go with two touchdowns rushing in Green Bays 49-23 win over Denver.
Michael Vick, Eagles, threw for a career-high 416 yards and two touchdowns and rushed for 75 yards in Philadelphias 24-23 loss to San Francisco.
Rookie Cam Newton, Panthers, threw for 374 yards and a touchdown and ran for two more in Carolinas 34-29 loss to Chicago.
Eli Manning, Giants, was 27 of 40 for 371 yards and two touchdowns in New Yorks 31-27 win over Arizona.
Colt McCoy, Browns, went 40 of 61 for 350 yards and one TD, setting club records for completions and attempts, in Clevelands 31-13 loss to Tennessee.
Drew Brees, Saints, threw for 351 yards and a touchdown in New Orleans 23-10 win over Jacksonville.
Tarvaris Jackson, Seahawks, threw for a career-high 319 yards and had his first three-touchdown game since 2008 in Seattles 30-28 loss to Atlanta.
Philip Rivers, Chargers, was 21 of 31 for 307 yards and one touchdown in San Diegos 26-16 win over Miami.
Matt Forte, Bears, ran for a career-high 205 yards in Chicagos 34-29 win over Carolina.
Arian Foster, Texans, rushed for 155 yards and a touchdown in Houstons 17-10 win over Pittsburgh.
Beanie Wells, Cardinals, rushed for a career-best 138 yards and three touchdowns in Arizonas 31-27 loss to the Giants.
Ryan Torain, Redskins, ran for 135 yards and a score in Washingtons 17-10 win over St. Louis.
Cedric Benson, Bengals, ran 19 times for 104 yards in Cincinnatis 23-20 win over Buffalo.
Calvin Johnson, Lions, caught eight passes for 96 yards and two touchdowns in Detroits 34-30 win over Dallas. Laurent Robinson, Cowboys, had seven catches for 116 yards.
Steve Smith, Panthers, had 181 yards receiving in Carolinas 34-29 loss to Chicago.
DeSean Jackson, Eagles, had 171 yards on six catches in Philadelphias 24-23 loss to San Francisco.
Wes Welker, Patriots, caught nine passes for 158 yards and a score in New Englands 31-19 win over Oakland.
Jordan Babineaux, Titans, returned an interception 97 yards for a TD in Tennessees 31-13 win over Cleveland.
Jason Babin, Eagles, had three sacks in Philadelphias 24-23 loss to San Francisco.
Chris Houston, Lions, had a 56-yard interception return for a touchdown, and teammate Bobby Carpenter had a 35-yarder in Detroits 34-30 win over Dallas.
Ryan Succop, Chiefs, had five field goals, including a career-long 54-yarder, to tie the team record in a 22-17 win over Minnesota.
Julius Peppers, Bears, blocked a field-goal attempt in Chicagos 34-29 win over Carolina.
Steelers quarterback Ben Roethlisberger (left foot) and Texans receiver Andre Johnson (right hamstring) were hurt in their game. Roethlisberger had plenty of company in the trainers room after Pittsburghs 17-10 loss at Houston. The Steelers also lost linebacker James Harrison (eye), running back Rashard Mendenhall (hamstring), defensive end Aaron Smith (foot) and linebacker Jason Worilds (left quad) during the game. It was a tough day for injuries all around the league, with Miami quarterback Chad Henne (left shoulder), Cleveland cornerback Joe Haden (sprained knee) and wide receiver Mohamed Massaquoi (shoulder) all leaving their games.
quote of the day
Its all about how you finish. The great ones finish, and hes going to be a great one. Receiver A.J. Green on fellow Bengals rookie Andy Dalton after the quarterback led Cincinnati to a comeback win over the previously unbeaten Bills.