Ben Roethlisberger, Steelers, threw for five touchdowns in Pittsburghs 38-17 win over Tennessee.
Drew Brees, Saints, threw for 359 yards and two touchdowns in New Orleans 30-27 win over Carolina.
Matt Cassel, Chiefs, was 21 of 29 for 257 yards and four touchdowns in Kansas Citys 28-24 win over Indianapolis.
Tom Brady, Patriots, threw for 321 yards and a touchdown in New Englands 30-21 win over the Jets.
Eli Manning, Giants, was 24 of 39 for 420 yards with three touchdowns and three interceptions in New Yorks 36-25 loss to Seattle.
Matt Schaub, Texans, threw for 416 yards and two touchdowns in Houstons 25-20 loss to Oakland.
Michael Vick, Eagles, was 26 of 40 for 315 yards and two touchdowns and rushed for 90 yards but had a career-worst four interceptions in Philadelphias 31-24 loss to Buffalo.
BenJarvus Green-Ellis, Patriots, rushed for a career-high 136 yards and two touchdowns in New Englands 30-21 win over the Jets.
Adrian Peterson, Vikings, rushed 29 times for 122 yards and three touchdowns in Minnesotas 34-10 win over Arizona.
Ryan Mathews, Chargers, ran for a career-best 125 yards in San Diegos 29-24 win over Denver. Willis McGahee, Broncos, also had 125 yards rushing.
Frank Gore, 49ers, rushed for 125 yards and a TD in San Franciscos 48-3 win over Tampa Bay.
Fred Jackson, Bills, had 196 yards from scrimmage and a touchdown in Buffalos 31-24 win over Philadelphia.
Jackie Battle, Chiefs, ran 19 times for 119 yards in Kansas Citys 28-24 win over Indianapolis.
Dwayne Bowe, Chiefs, caught seven passes for 128 yards and two touchdowns in Kansas Citys 28-24 win over Indianapolis. Pierre Garçon, Colts, had five catches for 125 yards and two scores.
Jimmy Graham, Saints, had eight catches for 129 yards in New Orleans 30-27 win over Carolina.
Doug Baldwin, Seahawks, had eight catches for 136 yards and a touchdown in Seattles 36-25 win over the Giants. Victor Cruz, Giants, had eight catches for 161 yards, including a 68-yard TD.
Jason Avant, Eagles, had 139 yards receiving in Philadelphias 31-24 loss to Buffalo.
Rookie A.J. Green, Bengals, caught five passes for 90 yards and a score in Cincinnatis 30-20 win over Jacksonville.
Nick Barnett, Bills, had two interceptions, returning one 31 yards for a touchdown, in Buffalos 31-24 win over Philadelphia.
Brandon Browner, Seahawks, returned an interception 94 yards for a score in Seattles 36-25 win over the Giants.
Carlos Rogers, 49ers, returned an interception 31 yards for a touchdown in San Franciscos 48-3 win over Tampa Bay.
Nick Novak, Chargers, kicked five field goals in San Diegos 29-24 win over Denver.
Seattle backup quarterback Charlie Whitehurst led the Seahawks to a comeback victory over the New York Giants after starter Tarvaris Jackson was sidelined midway through the third quarter. Jackson gained 11 yards on a designed run but came up holding his right shoulder and upper chest. Coach Pete Carroll said Jackson had a pectoral muscle problem and would undergo an MRI exam back in Seattle. Houston linebacker Mario Williams left the Texans loss to Oakland, also with an injured pectoral muscle.
quote of the day
Flat start. Flat finish. Flat middle. Everything. We didnt even get off the plane this time. We came out here this time and were a little punch bucket. Buccaneers coach Raheem Morris after Tampa Bay lost 48-3 in San Francisco.