EAST RUTHERFORD, N.J. Eli Manning came up with a near-record performance in throwing for 510 yards, and Andre Brown scored on a 2-yard run with 31 seconds left to lift the New York Giants to a wild 41-34 victory Sunday over the Tampa Bay Buccaneers.
Mannings yardage total was the second most for a Giants quarterback, and tied for the eighth highest in NFL history.
He threw three first-half interceptions, and came back with a monster 295 yards passing in the second, finishing 3 yards short of Phil Simms team record.
The Bucs (1-1) led by 11 points before the Super Bowl champions came back and avoided an 0-2 start.
Manning threw touchdowns of 23 yards to Hakeem Nicks, 80 to Victor Cruz and 33 to Martellus Bennett with 3:59 to play to give New York a 34-27 lead.
Cruz finished with 11 catches for 179 yards, both career highs, while Nicks had 10 catches for 199 yards, with the yardage a personal best. Only the 1951 Rams had a 500-yard passer and two 150-yard receivers in the same game.
Josh Freeman tied the game at 34-all with a 41-yard pass to Mike Williams, but Manning drove New York 80 yards in four plays to win it.
After the game, Giants coach Tom Coughlin yelled at Bucs coach Greg Schiano about a scrum when Manning took a knee after Michael Boley intercepted Freemans pass in the closing seconds.
Manning was not touched, but there was shoving and maybe even punches thrown. Coughlin contended that someone might have been hurt on a play in which teams typically go through the motions.
Cardinals 20, Patriots 18
FOXBOROUGH, Mass. Backup quarterback Kevin Kolb threw for one touchdown and ran for another, Stephen Gostkowski missed a potential winning field goal in the final seconds, and Ariizona moved to 2-0.
The Patriots took over when Vince Wilfork recovered a fumble at the Cardinals 30 with 1:01 left.
A 30-yard run into the end zone by former Chadron State star Danny Woodhead was nullified by a holding penalty against Rob Gronkowski.
New England then moved to the 24 before Tom Brady spiked the ball to stop the clock with 6 seconds left, but Gostkowski sent a 42-yard try wide to the left after hitting four earlier field goals.
The Cardinals won behind Kolb, filling in for John Skelton, who missed the game with a sprained right ankle. The Patriots (1-1) lost tight end Aaron Hernandez to an ankle injury in the first quarter.
Panthers 35, Saints 27
CHARLOTTE, N.C. Cam Newton threw for 253 yards and ran for a career-high 71 yards to hand New Orleans its first 0-2 start since 2007.
One week after tying a franchise low with 10 yards rushing in a loss to Tampa Bay, the Panthers ran for 219 yards and Newton, DeAngelo Williams and Mike Tolbert all scored on short touchdown runs.
Steve Smith overcame a sore knee to finish with 104 yards receiving the 39th 100-yard receiving game of his career and Jonathan Stewart hauled in a 17-yard touchdown reception for the Panthers (1-1).
Drew Brees had won his previous five starts against Carolina. He threw for 325 yards but was intercepted twice, including once by Charles Godfrey, who returned it 9 yards for a touchdown.
Eagles 24, Ravens 23
PHILADELPHIA Michael Vick scored on a 1-yard TD run with 1:55 left, helping Philadelphia overcome a slew of turnovers.
Rookie kicker Justin Tucker made field goals of 56, 51 and 48 yards for the Ravens, but Joe Flacco couldnt get Baltimore (1-1) in his range in the final minute.
Flacco overthrew Ray Rice on fourth-and-1 from the Ravens 46, and the Eagles ran out the clock.
Vick threw four interceptions at Cleveland last week, but rallied the Eagles (2-0) to a 17-16 win.
He did it again, though the replacement officials almost made a costly mistake.
Down 23-17, the Eagles started at their 20 with 4:43 left. After two completions to Brent Celek, a 19-yarder to Clay Harbor and a roughing-the-passer penalty, the ball was at the 3.
Vick threw incomplete as he was being hit by Haloti Ngata, but the play was ruled a fumble. It was recovered by the Ravens, but replay overturned the turnover, and Vick scored on the next play.
Colts 23, Vikings 20
INDIANAPOLIS Adam Vinatieri made a 53-yard field goal with 8 seconds left to give Andrew Luck his first NFL victory.
Minnesota (1-1) rallied from a two-touchdown deficit in the final 5½ minutes and tied the score on a 6-yard TD pass from Christian Ponder to Kyle Rudolph with 31 seconds left.
But that was too much time for Luck, who had thrown for two touchdowns. He started with back-to-back 20-yard completions, then drew the Vikings offside before spiking the ball with 12 seconds to go.
Vinatieri, the best clutch kicker in NFL history, knocked the 53-yarder through the uprights to win it.
Luck finished 20 of 31 for 224 yards.
Dolphins 35, Raiders 13
MIAMI Reggie Bush ran for 172 yards and two touchdowns, and Miami won a home opener for the first time since 2005.
Ryan Tannehill threw his first NFL touchdown pass, ran for another and avoided any turnovers after tossing three interceptions in his pro debut a week earlier.
The Dolphins improved to 1-1, and Joe Philbin earned a sideline drenching for his first victory as a head coach. The Raiders, under new coach Dennis Allen, are 0-2 for the first time since 2007.
Bush broke four tackles on a 23-yard touchdown run that put Miami ahead to stay in the third quarter. After Miami forced a punt, Bush struck again, this time on a 65-yard scoring run.
Texans 27, Jaguars 7
JACKSONVILLE, Fla. Arian Foster ran for 110 yards and a touchdown, Ben Tate added 74 yards and two scores, and Houston dominated from the start.
The Texans improved to 2-0 for the third consecutive season by winning their fourth in a row against the AFC South rival Jaguars, who started 0-2 for the third time in the last five years.
Jacksonville, which has never had a winning record after dropping its first two games, was far from competitive in the latest meeting.
The Texans gained 242 yards in the first half while building a 17-0 lead. Foster ran for 69 yards and a score. Tate added 49 and a touchdown. Matt Schaub, using mostly short throws, picked apart Jacksonvilles defense.
The Jaguars finished with a franchise-low 117 yards.
Bills 35, Chiefs 17
ORCHARD PARK, N.Y. C.J. Spiller scored twice and had 123 yards rushing in sparking Buffalo.
Ryan Fitzpatrick threw two touchdown passes, including a 49-yarder to Stevie Johnson, and Leodis McKelvin scored on an 88-yard punt return the second longest in team history in the Bills home opener.
Buffalos high-priced defense had five sacks and forced three turnovers as the Bills bounced back from a season-opening 48-28 loss to the Jets last week.
Dwayne Bowe scored both touchdowns for Kansas City both in the final seven minutes to make the score respectable. The Chiefs are 0-2 for the sixth time in seven years.
Bengals 34, Browns 27
CINCINNATI Adam Pacman Jones returned Clevelands first punt 81 yards for a touchdown, and Andy Dalton matched his career high with three touchdown passes.
The Bengals (1-1) have won 13 of the last 16 against the Browns (0-2), who got impressive games from their rookie quarterback and running back but still couldnt get a win.
Jones put the Bengals ahead to stay with his fifth career punt return for a touchdown. Dalton threw three TD passes for the second time in his career, including a short reception that Andrew Hawkins turned into a 50-yard score in the fourth quarter.
Cleveland quarterback Brandon Weeden rebounded from one of the worst debuts in NFL history by throwing for two touchdowns. Trent Richardson became the first Browns rookie to run for 100 yards and score on a run and a pass.
Steelers 27, Jets 10
PITTSBURGH Ben Roethlisberger passed for 275 yards and two touchdowns, and Pittsburgh smothered the Jets in the second half.
Roethlisberger completed 24 of 31 passes. He hit Heath Miller for a 1-yard score to give the Steelers (1-1) the lead late in the first half, then found Mike Wallace for a 37-yard strike early in the third quarter to break the game open.
Isaac Redman added a late 2-yard touchdown run for Pittsburgh, which had little trouble avoiding its first 0-2 start in a decade.
The Jets (1-1) did little offensively after a pair of early scoring drives. Mark Sanchez passed for 138 yards and a touchdown, but New York hardly looked like the offensive juggernaut that piled up points in a 48-28 opening-week blowout win over Buffalo.
Rams 31, Redskins 28
ST. LOUIS Sam Bradford threw for 310 yards and three touchdowns, and Danny Amendola caught 15 passes for 160 yards in rallying St. Louis to victory.
The Rams made their comeback after running back Steven Jackson left the game after drawing an unsportsmanlike conduct penalty in the second quarter. Later, coach Jeff Fisher said Jackson left because of a groin injury.
Griffin led the Redskins (1-1) to a 21-6 lead, but the Rams (1-1) came back thanks to the pass-catching of Amendola. The receiver tied an NFL record with 12 first-half receptions and caught a 1-yard touchdown pass to cut the lead to 21-13 at the half. Bradford had second-half scoring passes of 34 yards to Brandon Gibson and 1 yard to Matt Mulligan.
Griffin ran for two touchdowns and passed for a third for Washington (1-1).
Seahawks 27, Cowboys 7
SEATTLE Marshawn Lynch ran for 122 yards and a 3-yard touchdown in the fourth quarter, and Seattles special teams came up with two huge first-quarter plays that led to 10 points.
Michael Robinson forced Felix Jones to fumble on the opening kickoff that led to a short field goal, and Malcolm Smith blocked Chris Jones punt which Jeron Johnson returned for a touchdown to give Seattle (1-1) a 10-0 lead in less than 5 minutes.
Rookie Russell Wilson threw for 151 yards and directed a 90-yard scoring drive in the third quarter capped by a 22-yard touchdown strike to Anthony McCoy to give Seattle a 20-7 lead.
Tony Romo threw a 22-yard touchdown to Miles Austin in the second quarter, but that was the only sustained drive the Cowboys (1-1) could mount on the Seahawks stout defense.
Chargers 38, Titans 10
SAN DIEGO Tight end Dante Rosario had three touchdown catches for the first time in his NFL career, and San Diegos defense harassed Jake Locker all day.
Before the game, the Chargers (2-0) retired Junior Seaus No. 55. Seau, the hard-hitting, first-pumping leader of the Chargers for 13 seasons, committed suicide May 2.
With Antonio Gates inactive due to sore ribs, the Chargers turned to Rosario. He responded with touchdown catches of 11, 4 and 15 yards from Philip Rivers. He had only five career scoring catches coming in, including a game-winner against San Diego in the 2008 season opener while with Carolina.
San Diegos winning streak against the Titans (0-2) dates to 1993, when the franchise was still the Houston Oilers.
Rivers was 24 of 32 for 284 yards. Malcom Floyd had six catches for 109 yards and Rosario four catches for 48 yards.
49ers 27, Lions 19
SAN FRANCISCO San Franciscos stingy defense denied Matthew Stafford another milestone, Vernon Davis caught touchdown passes of 21 and 23 yards from Alex Smith, and the 49ers beat the Detroit Lions.
Smith completed 20 of 31 throws for 226 yards and extended his franchise-record streak of passes without an interception to 216, leading the NFC West favorite Niners (2-0) to their ninth consecutive win in the series. Smith took a hard hand to the helmet from John Wendling late and bloodied his nose.
The 49ers ran their home winning streak against the Lions (1-1) to 12 and there was no heated greeting afterward this time. Coaches Jim Harbaugh and Jim Schwartz met before the game with a friendly hello and handshake.