Denard Robinson, Michigan, rushed 24 times for 235 yards, threw for a touchdown and helped lead the Wolverines to a 44-13 rout at Purdue.
Josh Nunes, Stanford, threw for a career-high 360 yards and two TDs in the No. 18 Cardinals 54-48 win over Arizona.
Matt Scott, Arizona, set school records by completing 45 of 69 passes while throwing for 491 yards and three TDs in the Wildcats 54-48 loss to No. 18 Stanford.
Josh Woodrum, Liberty, threw for 373 yards and three TDs in a 42-35 win over Gardner-Webb.
Tyler Van Tubbergen, Western Michigan, threw five TD passes and ran for a score in a 52-14 victory over Massachusetts.
Colton Chapple, Harvard, threw three of his four TD passes to Andrew Berg in a 45-13 victory over Cornell.
Mike Colvin, Lehigh, passed for 415 yards and four TDs and ran for a fifth score in a 35-14 win over Columbia.
Jamal Jackson, Appalachian State, threw four TD passes, ran for one more and had 398 all-purpose yards to lead the Mountaineers to a 35-23 win over Elon.
Kade Bell, Jacksonville, threw three of his four TD passes to Andrew Robustelli in a 38-17 victory over Morehead State.
Joe Southwick threw for three touchdowns, and Boise State took advantage of five turnovers to breeze past Southern Mississippi 40-14.
Mike Gillislee, Florida, ran for a career-high 146 yards and two touchdowns in No. 10 Floridas 14-6 win over LSU.
John Hubert, Kansas State, ran for 101 yards and four touchdowns on just 10 carries in No. 7 Kansas States 56-16 win over Kansas.
Tajh Boyd, Clemson, threw for a career-high 397 yards to lead the 15th-ranked Tigers over Georgia Tech 47-31.
Trent Steelman, Army rushed for 141 yards and scored three times, including a decisive 29-yard touchdown run with 45 seconds left, and the Black Knights beat Boston College 34-31.
Jared Barnett threw three touchdowns to Josh Lenz, who later had a scoring toss of his own on a trick play, as Iowa State ended No. 15 TCUs FBS-best 12-game win streak with a 37-23 win.
Gio Bernard, North Carolina, rushed for a career-high 262 yards and a touchdown to help the Tar Heels beat Virginia Tech 48-34.
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No. 3 LSU was one of four undefeated teams to lose in Saturdays early games:
Iowa State handed No. 15 TCU its first loss.
Penn State made it four consecutive victories by beating No. 24 Northwestern 39-28. The Wildcats were trying to go to 6-0.
Also, unranked Texas Tech lost 41-20 at home against No. 17 Oklahoma.
9: Sacks, including five by Michael Cole, in Maines 26-3 win over Delaware.
293: Career receptions by Dukes Conner Vernon to set the Atlantic Coast Conference record.
500: Wins by Bowling Green in its 94 seasons after beating Akron 24-10. The Falcons have 349 losses and 51 ties.
614: Yards rushing by Georgia Southern in its 45-13 win over Western Carolina.
3,905: Career yards rushing by Michigans Denard Robinson, setting a Big Ten record for a quarterback and breaking a tie with Kent States Josh Cribbs to move into fifth place in NCAA history.