Andre Johnson caught a screen pass from Matt Schaub and ran 48 yards for the winning touchdown in overtime as the Houston Texans rallied to beat Jacksonville 43-37 on Sunday.
Schaub threw a career-high five touchdown passes, completed a franchise-record 43 passes and finished with 527 yards passing, second most in NFL history. Warren Moon also threw for 527 yards for the Houston Oilers in December 1990 against Kansas City.
Norm Van Brocklin holds the record with 554 for the Rams in 1951.
Johnson caught 14 passes for 273 yards, both career highs. The Texans (9-1) won an overtime game for the first time at Reliant Stadium.
Falcons 23, Cardinals 19
ATLANTA Matt Ryan overcame a career-worst five interceptions, guiding Atlanta to its only offensive touchdown in the fourth quarter in a sloppy win.
The Falcons (9-1) turned it over a total of six times, but Michael Turner scored on a 1-yard run with 6:40 remaining to give Atlanta its first lead of the game. Ryan set up the score with four completions for 64 yards, including a 9-yarder to Tony Gonzalez on third-and-5 at the Arizona 10.
Packers 24, Lions 20
DETROIT Aaron Rodgers threw two touchdown passes, including a 22-yarder to Randall Cobb with 1:55 left to lift Green Bay.
Mason Crosby made a 39-yard field goal with 19 seconds to go after missing two field goals earlier in the game.
Matthew Stafford couldn't put the Lions ahead on either of their last two drives in a game he'd like to forget.
Stafford threw two interceptions one of which was returned 72 yards by Green Bay safety M.D. Jennings for a go-ahead score in the third quarter and lost a fumble.
Cowboys 23, Browns 20, OT
ARLINGTON, Texas Dan Bailey kicked a 38-yard field goal in overtime, and Dallas overcame a critical fumble by Tony Romo that sparked a wild ending.
Bailey's winning kick with 6:07 remaining in OT came after both teams punted once in the first overtime game at Cowboys Stadium. Bailey hit a tying 32-yard field goal with 2 seconds left in regulation.
Dallas (5-5) rallied from a 13-0 halftime deficit and went ahead 17-13 on Romo's 28-yard pass to Dez Bryant.
A fumble by Browns rookie Brandon Weeden on a sack appeared to put the Cowboys in control, but Romo gave it right back with a fumble on another sack.
The Cowboys made one goal-line stand in the final minutes, but the Browns got another chance and went ahead 20-17 on Weeden's 17-yard pass to Benjamin Watson.
Buccaneers 27, Panthers 21, OT
CHARLOTTE, N.C. Josh Freeman threw a 15-yard touchdown pass to Dallas Clark in overtime to cap a comeback.
It was Freeman's third touchdown pass of the game for the Buccaneers (6-4).
Carolina appeared to have the game in hand after a 29-yard touchdown pass from Cam Newton to Brandon LaFell put the Panthers (2-8) up 21-10 with 4:34 left in the game. But after a 40-yard field goal by Connor Barth, the Panthers were forced to punt, and Freeman led the Bucs 80 yards on seven plays in 50 seconds with no timeouts.
Patriots 59, Colts 24
FOXBOROUGH, Mass. The Patriots used three scoring passes from Tom Brady, two touchdowns on interception returns and another on a punt return to match a team single-game scoring record.
The first matchup between three-time Super Bowl winner Brady and star rookie Andrew Luck was no match..
The 59 points equals the team mark set in a 59-0 win over the Tennessee Titans on Oct. 18, 2009.
Saints 38, Raiders 17
OAKLAND, Calif. Drew Brees threw three touchdown passes, and Malcolm Jenkins returned an interception for another score to get the Saints back to .500.
Lance Moore caught two touchdown passes, and Mark Ingram ran for a score as the Saints (5-5) won for the fifth time in six games and are in position to make a late-season playoff run despite the season-long distraction from the bounty scandal.
Brees finished 20 of 27 for 219 yards, extending his own records by throwing a touchdown in his 53rd consecutive game and completing 20 passes for the 46th consecutive game.
Redskins 31, Eagles 6
LANDOVER, Md. Robert Griffin III threw four touchdown passes, and Washington broke a three-game losing streak.
Griffin completed 14 of 15 passes for 200 yards and also ran 11 times for 85 yards. He threw for scores of 6, 49, 61 and 17 yards one in each quarter.
Philadelphia's Nick Foles was 21 of 46 for 204 yards in his first NFL start, and his first two series ended with interceptions. Foles was starting in place of Michael Vick, who suffered a concussion in last week's loss to Dallas.
The Redskins improved to 4-6. The Eagles (3-7) have dropped six in a row, accelerating the countdown toward the possible end of Andy Reid's 14-year tenure as coach.
Jets 27, Rams 13
ST. LOUIS Mark Sanchez directed a turnover-free offense, and Bilal Powell ran for the first two touchdowns of his career as the Jets ended a three-game losing streak.
Chaz Schilens scored on a 25-yard reception, and Nick Folk kicked a pair of 51-yard field goals for the Jets (4-6), who were outscored 58-16 the previous two games. The Jets overcame a controversial practice week with several anonymous players quoted in a newspaper report disparaging the ability of backup quarterback Tim Tebow, who had a handful of snaps but was no factor.
Bengals 28, Chiefs 6
KANSAS CITY, Mo. Andy Dalton threw for 230 yards and accounted for three touchdowns, and A.J. Green caught a touchdown pass in his ninth consecutive game.
Green finished with six catches for 91 yards in another dazzling performance, Mohamed Sanu had a scoring grab, and BenJarvus Green-Ellis ran for 101 yards and a touchdown as the Bengals (5-5) won their second straight following a four-game losing streak.
Jamaal Charles had 87 yards rushing for Kansas City (1-9), but that was the only highlight for a team that lost its seventh in a row amid a quiet crowd at Arrowhead Stadium.
Ravens 13, Steelers 10
PITTSBURGH Jacoby Jones returned a punt for a touchdown, Justin Tucker kicked two field goals, and the Baltimore Ravens took control of the AFC North with a critical victory over the Pittsburgh Steelers on Sunday night.
The Ravens (8-2) moved two games in front of the Steelers (6-4) by shutting down Pittsburghs offense, which sputtered without injured quarterback Ben Roethlisberger.
Byron Leftwich, making his first start in more than three years, completed 18 of 39 passes for 201 yards and an interception. He ran for a score but also was sacked three times.